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CAS No. 68302-57-8 | Amlexanox

Name: Amlexanox CAS No. 68302-57-8 MF:C16H14N2O4 MW:298.29 Purity:98% Package: 10g,25g,50g,100g,250g Worldwide Delivery

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Biochemicals

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Product introduction

Introduction and application of CAS No. 68302-57-8 | Amlexanox

Synonyms:5h-(1)benzopyrano(2,3-b)pyridine-3-carboxylicacid,2-amino-7-(1-methylethyl)-5;

amoxanox;

RARECHEMALBO1376;

AMLEXANOX;

2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]benzopyrano[2，3-bJpyridine-3-carboxylicacid;

Aphthasol

Specification:

ITEMS	SPECIFICATION
CAS	68302-57-8
MF	C16H14N2O4
MW	298.29
Melting point	>300C
Boiling point	570.0±50.0 °C
Density	1.408±0.06 g/cm3
Acidity coefficient	3.95±0.20
Color	white to beige
Solubility	Solubility in DMSO is 10mg/mL, clear
Form	Powder
Storage condition	-20°C

Chemical properties:

White to yellowish-white crystals or crystalline powder, odorless and tasteless. Easily soluble in dimethyl sulfoxide, relatively soluble in dimethylformamide, insoluble in tetrahydrofuran, extremely insoluble in methanol, ethanol or chloroform, almost insoluble in ether, acetonitrile or water. Melting point＞300℃. Acute toxicity LD50 for mice and rats (mg/kg): 2320~2370, about 10,000 orally.

use:

It has inhibitory effects on histamine free reaction, inhibition of leukotriene production and anti-leukotriene effects, thereby producing anti-asthma effects. For the treatment of bronchial asthma and allergic rhinitis.Used to treat oral ulcers

Production method:

3-cyano 6-isopropylbenzopyrone (I) is heated in an aqueous solution containing morpholine and dimethylformamide at 60°C to obtain compound (II). Then it is condensed and cyclized with monoethyl malonate amide, and then hydrolyzed to obtain ammonia.

Package and transportation :

Package: 10g,25g,50g,100g,250g